SCHEMBL11269700

SCHEMBL11269700

CCOC(C)O[Si](CCBr)(OC(C)OCC)OC(C)OCC

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11122070 0.82 LMNA (0.50) LMNATHRB
SCHEMBL11272057 0.78 LMNA (0.46) LMNATHRB
SCHEMBL11268872 0.78 LMNA (0.46) LMNATHRB
SCHEMBL11263771 0.77
SCHEMBL7072220 0.77 LMNA (0.55) LMNATHRB
SCHEMBL9164105 0.74
SCHEMBL7991095 0.73 LMNA (0.50) LMNATHRB
SCHEMBL93470 0.72 LMNA (0.44) LMNA
SCHEMBL49466 0.71 LMNA (0.61) LMNATHRB
SCHEMBL11268621 0.69 LMNA (0.41) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4332612-A N-METHYL-2-PYRROLIDONE AND A HALOALKYL SILANE GAF CORPORATION (US) 1982-06-01 US disclosed