Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.67 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.67 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | PRKCI | P41743 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482909 | 0.83 | IDH1 (0.56) | POLBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL27863267 | 0.83 | PRKCI (0.56) | POLBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL17481522 | 0.82 | ESR1 (0.59) | POLBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL11131965 | 0.82 | POLB (0.69) | POLBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL917999 | 0.80 | CDK1 (0.56) | POLBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL29565648 | 0.80 | PRKCI (1.00) | POLBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL6266901 | 0.80 | POLB (0.67) | POLBKDM4EMEN1ALDH1A1MAPT | |
| Bromide SCHEMBL11132004 | 0.80 | POLB (0.67) | POLBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL111109 | 0.80 | PRKCI (1.00) | POLBKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL5805285 | 0.79 | HTT (0.59) | POLBKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322304-A | ANTIOXIDANTS | PHILLIPS PETROLEUM COMPANY (US) | 1982-03-30 | — | — | US | claimed |
| US-4322304-A | ANTIOXIDANTS | PHILLIPS PETROLEUM COMPANY (US) | 1982-03-30 | — | — | US | disclosed |