Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267823 | 0.82 | ACE (0.48) | ACE | |
| SCHEMBL11268825 | 0.81 | ACE (0.48) | ACE | |
| SCHEMBL11262147 | 0.78 | ACE (0.65) | ACE | |
| SCHEMBL11263934 | 0.78 | ACE (0.65) | ACE | |
| SCHEMBL11262595 | 0.77 | ACE (0.47) | ACE | |
| SCHEMBL11262600 | 0.77 | ACE (0.47) | ACE | |
| SCHEMBL11268649 | 0.75 | ACE (0.45) | ACE | |
| SCHEMBL10552615 | 0.74 | ACE (0.62) | ACE | |
| SCHEMBL11450170 | 0.74 | ACE (0.37) | ACE | |
| SCHEMBL11450169 | 0.74 | ACE (0.37) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330548-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-05-18 | — | — | US | disclosed |
| US-4296113-A | FOR TREATING HYPERTENSION BY INHIBITING ANGIOTENSIN CONVERTING ENZYME | E. R. SQUIBB & SONS, INC. (US) | 1981-10-20 | — | — | US | disclosed |