Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 9/20 | 0.55 |
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269758 | 1.00 | KDM4E (0.69) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11263116 | 0.85 | KDM4E (0.71) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL7649097 | 0.83 | KDM4E (0.64) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL7649090 | 0.83 | KDM4E (0.64) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL12706012 | 0.78 | KDM4E (0.72) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11276494 | 0.78 | KDM4E (0.63) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11745903 | 0.77 | KDM4E (0.71) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL13767922 | 0.77 | KDM4E (0.70) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11263845 | 0.77 | KDM4E (0.66) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL29669640 | 0.76 | KDM4E (0.70) | KDM4EPOLBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321396-A | Copolymerizable, ultraviolet light absorber allyloxy-2-(2H-benzotriazol-2-yl)-4-alkylbenzenes | GAF CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |