Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649097 | 1.00 | KDM4E (0.64) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11269773 | 0.83 | KDM4E (0.69) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11269758 | 0.83 | KDM4E (0.69) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11263116 | 0.79 | KDM4E (0.71) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL7647887 | 0.74 | KDM4E (0.45) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL7647889 | 0.74 | KDM4E (0.45) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL12706012 | 0.73 | KDM4E (0.72) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL19194642 | 0.72 | KDM4E (0.67) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL19194534 | 0.72 | KDM4E (0.67) | KDM4EPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL15842418 | 0.72 | KDM4E (0.70) | KDM4EPOLBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127881-B1 | Alkylation process and novel hydroxyphenylbenztriazoles | DSM IP ASSETS BV (NL) | 2012-08-08 | — | — | EP | disclosed |
| US-6489486-B2 | 2-(BENZOTRIAZOL-2-YL)-4-METHYL-6-(1-OCTEN-3-YL)-PHENOL, FOR EXAMPLE; MADE BY REACTING A HALOALKENYL OR SULFONYLOXYALKENYL WITH 2-(BENZOTRIAZOL-2-YL)-4-ALKYL-6-PHENOL AND HEATING THE RESULTING INTERMEDIATE | ROCHE VITAMINS INC. | 2002-12-03 | — | — | US | disclosed |
| US-20010023293-A1 | 2-hydroxyphenyl benzotriazoles as uv-a/b filters | ROCHE VITAMINS INC. | 2001-09-20 | — | — | US | disclosed |
| EP-1127881-A1 | Alkylation process and novel hydroxyphenylbenztriazoles | F. HOFFMANN-LA ROCHE AG (CH) | 2001-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010023293-A1 | 2-hydroxyphenyl benzotriazoles as uv-a/b filters | CYP1B1, SULT2A1, TPST2 | KDM4E 956/4885POLB 743/4885NPC1 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.