Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46283 | 0.84 | TSHR (0.67) | TSHRPARP1HTR1ADRD3ADRA2A | |
| SCHEMBL21974861 | 0.84 | TSHR (0.67) | TSHRPARP1HTR1ADRD3ADRA2A | |
| SCHEMBL5852993 | 0.78 | TSHR (0.54) | TSHRPARP1HTR2BTAAR1 | |
| SCHEMBL938854 | 0.78 | TSHR (0.54) | TSHRPARP1HTR2BTAAR1 | |
| SCHEMBL16412704 | 0.78 | TSHR (0.54) | TSHRPARP1HTR2BTAAR1 | |
| SCHEMBL25831541 | 0.78 | TSHR (0.54) | TSHRPARP1HTR2BTAAR1 | |
| SCHEMBL4356953 | 0.77 | MEN1 (0.36) | TSHRHTR1ADRD3DRD2TAAR1 | |
| SCHEMBL25261475 | 0.74 | TSHR (0.54) | TSHRPARP1HTR1ADRD3ADRA2A | |
| SCHEMBL7784351 | 0.74 | TSHR (0.54) | TSHRPARP1DRD3DRD2HTR2B | |
| SCHEMBL937187 | 0.74 | TSHR (0.54) | TSHRPARP1HTR2BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352938-A | ADHESION OF POLYPROPYLENE TO GLASS FIBERS OR TIRE CORDS TO RUBBER | HERCULES INCORPORATED (US) | 1982-10-05 | — | — | US | disclosed |
| US-3971743-A | CROSSLINKING POLYMERS | HERCULES INCORPORATED (US) | 1976-07-27 | — | — | US | disclosed |
| US-3971627-A | MODIFIED POLYESTER, POLYAMIDE, POLYCARBONATE, POLYOLEFIN OR RAYON TIRE CORD | HERCULES INCORPORATED (US) | 1976-07-27 | — | — | US | disclosed |
| US-3941751-A | Epoxy-azido compounds | HERCULES INCORPORATED (US) | 1976-03-02 | — | — | US | disclosed |