Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.50 |
| ▸ | IL2 | P60568 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272106 | 0.79 | TP53 (0.53) | TP53SMN1; SMN2EPHX2MEN1KMT2A | |
| SCHEMBL9135140 | 0.78 | TRPV1 (0.51) | IL2MEN1KMT2AMAPT | |
| SCHEMBL8660878 | 0.78 | TRPV1 (0.46) | TP53SMN1; SMN2EPHX2IL2MEN1 | |
| SCHEMBL29608194 | 0.76 | MEN1 (0.54) | IL2MEN1KMT2AUSP2MAPT | |
| SCHEMBL352658 | 0.76 | MEN1 (0.54) | IL2MEN1KMT2AUSP2MAPT | |
| SCHEMBL11254846 | 0.76 | EPHX2 (0.46) | EPHX2IL2MEN1KMT2AUSP2 | |
| SCHEMBL11271774 | 0.75 | IL2 (0.49) | IL2MEN1KMT2AEPAS1USP2 | |
| SCHEMBL7607258 | 0.74 | MAPT (0.62) | TP53SMN1; SMN2EPHX2MEN1KMT2A | |
| SCHEMBL30499684 | 0.74 | MAPT (0.62) | TP53SMN1; SMN2EPHX2MEN1KMT2A | |
| Penfluron SCHEMBL117735 | 0.74 | EPHX2 (0.60) | EPHX2IL2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336264-A | 1-Benzoyl-3-(isoxazolyl or benzisoxazolyl)-ureas and insecticidal use thereof | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | claimed |