Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 16/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270117 | 1.00 | TBXAS1 (0.73) | TBXAS1L3MBTL1ALDH1A1 | |
| SCHEMBL11271836 | 0.78 | TBXAS1 (0.71) | TBXAS1 | |
| SCHEMBL11271842 | 0.78 | TBXAS1 (0.71) | TBXAS1 | |
| SCHEMBL11278011 | 0.77 | TBXAS1 (0.64) | TBXAS1 | |
| SCHEMBL26033595 | 0.76 | TBXAS1 (0.48) | TBXAS1ALDH1A1 | |
| SCHEMBL11277829 | 0.74 | TBXAS1 (0.74) | TBXAS1L3MBTL1 | |
| SCHEMBL16090981 | 0.73 | TBXAS1 (0.47) | TBXAS1 | |
| SCHEMBL11275411 | 0.73 | TBXAS1 (0.67) | TBXAS1 | |
| SCHEMBL11268220 | 0.72 | TBXAS1 (0.69) | TBXAS1 | |
| SCHEMBL11275678 | 0.72 | TBXAS1 (1.00) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4355170-A | ANTIINFLAMMATORY, HYPERTENSIVE, ANTIASTHMATIC AGENTS, A THROMBOXANE SYNTHETASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4256757-A | ANTIINFLAMMATORY AND HYPOTENSIVE AGENTS; THROMBOSIS; ASTHMA; NERVOUS SYSTEM DISORDERS | ONO PHARMACEUTICAL CO., LTD. | 1981-03-17 | — | — | US | disclosed |