Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258631 | 0.95 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1QPCTALDH1A1 | |
| SCHEMBL11269437 | 0.93 | QPCT (0.49) | CYP11B1CYP11B2CYP19A1QPCTALDH1A1 | |
| SCHEMBL11252384 | 0.90 | QPCT (0.46) | CYP11B1CYP11B2CYP19A1QPCTALDH1A1 | |
| SCHEMBL11270311 | 0.89 | CYP19A1 (0.50) | CYP11B1CYP11B2CYP19A1QPCT | |
| SCHEMBL11251892 | 0.88 | QPCT (0.47) | CYP11B1CYP11B2CYP19A1QPCTALDH1A1 | |
| SCHEMBL11260158 | 0.88 | CYP19A1 (0.42) | CYP19A1 | |
| SCHEMBL11272520 | 0.87 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1ALDH1A1POLB | |
| SCHEMBL11260572 | 0.87 | HMOX1 (0.52) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11264249 | 0.87 | CYP2A6 (0.52) | CYP11B1CYP11B2CYP19A1ALDH1A1 | |
| SCHEMBL11259165 | 0.87 | CYP19A1 (0.49) | CYP11B1CYP11B2CYP19A1QPCTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |