SCHEMBL11270485

SCHEMBL11270485

CCCCCCCCCCCC1OC(CCCCCCCCCCC)OC(CCCCCCCCCCC)O1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
TSHR P16473 2/20 0.47
THRB P10828 1/20 0.47
EPHX1 P07099 1/20 0.46
PRKD3 O94806 2/20 0.40
PRKCG P05129 2/20 0.40
PRKCB P05771 2/20 0.40
PRKCA P17252 2/20 0.40
PRKCH P24723 2/20 0.40
PRKCI P41743 2/20 0.40
PRKCE Q02156 2/20 0.40
PRKCQ Q04759 2/20 0.40
PRKCZ Q05513 2/20 0.40
PRKCD Q05655 2/20 0.40
PRKD1 Q15139 2/20 0.40
CYP1A2 P05177 2/20 0.38
ENPP2 Q13822 1/20 0.38
LPAR2 Q9HBW0 1/20 0.38
EBP Q15125 1/20 0.37
SIGMAR1 Q99720 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11263375 1.00 ALDH1A1 (0.56) ALDH1A1TSHRTHRBEPHX1PRKD3
SCHEMBL11257323 0.97 ALDH1A1 (0.52) ALDH1A1TSHRTHRBEPHX1PRKD3
SCHEMBL11264394 0.88 ALDH1A1 (0.42) ALDH1A1TSHRTHRBEPHX1PRKD3
SCHEMBL5945074 0.87 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1PRKD3
SCHEMBL5945072 0.87 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1PRKD3
SCHEMBL3505674 0.87 ALDH1A1 (0.50) ALDH1A1TSHRTHRBEPHX1PRKD3
SCHEMBL23211229 0.83 ALDH1A1 (0.46) ALDH1A1TSHRTHRBEPHX1PRKD3
SCHEMBL1456098 0.82
SCHEMBL8186591 0.82 ALDH1A1 (0.56) ALDH1A1TSHRTHRBEPHX1CYP1A2
SCHEMBL9849169 0.82 ALDH1A1 (0.56) ALDH1A1TSHRTHRBEPHX1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4330474-A USING SILICA GEL AS CYCLIZATION CATALYST CHEMISCHE WERKE HUELS, A.G. (DE) 1982-05-18 US disclosed