SCHEMBL11270567

SCHEMBL11270567

CC(C)C(C=C(Cl)Cl)C(C(=O)OCc1cccc(Oc2ccc(Cl)cc2)n1)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 19/20 0.42
MRGPRX4 Q96LA9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11279540 0.92 P2RX3 (0.43) P2RX3MRGPRX4
SCHEMBL11267837 0.91 SCN9A (0.37) P2RX3
SCHEMBL11274667 0.90 P2RX3 (0.34) P2RX3MRGPRX4
SCHEMBL11282335 0.89 P2RX3 (0.41) P2RX3MRGPRX4
SCHEMBL11284589 0.83 P2RX3 (0.43) P2RX3
SCHEMBL11273182 0.83 P2RX3 (0.38) P2RX3
SCHEMBL11267887 0.82 SCN9A (0.38) P2RX3
SCHEMBL11477999 0.82 P2RX3 (0.45) P2RX3MRGPRX4
SCHEMBL11282323 0.82 P2RX3 (0.35) P2RX3MRGPRX4
SCHEMBL11275035 0.81 P2RX3 (0.35) P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4338326-A PESTICIDES UNION CARBIDE CORPORATION (US) 1982-07-06 US disclosed