SCHEMBL11270823

SCHEMBL11270823

C=CC(=O)C(C)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.36
TSHR P16473 3/20 0.35
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP1A2 P05177 1/20 0.34
CACNA2D1 P54289 2/20 0.34
CACNB3 P54284 1/20 0.34
CACNA1C Q13936 1/20 0.34
PGR P06401 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
CACNA2D2 Q9NY47 1/20 0.34
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
REN P00797 1/20 0.33
ACE P12821 1/20 0.33
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27694676 0.81 ALDH1A1 (0.46) TSHRTDP1ALDH1A1
SCHEMBL27549835 0.80 SLC22A6 (0.39) SLC22A6LMNATDP1CYP1A2CACNA2D1
SCHEMBL28770632 0.80 FOLH1 (0.39) TDP1CYP1A2CACNA2D1CACNB3CACNA1C
SCHEMBL23420246 0.77 CYP2C19 (0.41) TSHRTDP1ALDH1A1
SCHEMBL5177571 0.77 TSHR (0.41) TSHRTDP1ALDH1A1
SCHEMBL27987434 0.77 TSHR (0.39) SLC22A6TSHRSMN1; SMN2
SCHEMBL11413301 0.76 ALDH1A1 (0.35) TSHRTDP1ALDH1A1
SCHEMBL2407813 0.76 TSHR (0.34) TSHR
SCHEMBL28770373 0.76 KDM4E (0.41) TSHRLMNAALOX15HSD17B10
SCHEMBL11051391 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112334864-B Touch sensor module, window stack structure including the same, and image display device including the same 东友精细化工有限公司 2024-07-12 CN disclosed
CN-112424677-B Flexible display module and image display apparatus including the same 东友精细化工有限公司 2024-05-28 CN disclosed
CN-116997464-A Glass laminate article and adhesive composition therefor 康宁股份有限公司 2023-11-03 CN disclosed
CN-116908953-A Polarizing plate and image display device including the same 东友精细化工有限公司 2023-10-20 CN disclosed
EP-0049589-A1 Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines E.R. Squibb & Sons, Inc. (US) 1982-04-14 EP disclosed
US-4311705-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1982-01-19 US disclosed