SCHEMBL11270919

SCHEMBL11270919

CCCCCCC1(CCCCCC)N=c2ccccc2=N1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 5/20 0.40
MMP9 P14780 5/20 0.40
MMP3 P08254 1/20 0.40
MMP8 P22894 2/20 0.39
MMP13 P45452 2/20 0.39
KCNH2 Q12809 1/20 0.38
SLC9A1 P19634 3/20 0.38
GAA P10253 2/20 0.36
MEN1 O00255 1/20 0.36
ALOX12 P18054 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 2/20 0.36
OPRM1 P35372 1/20 0.36
OPRD1 P41143 1/20 0.36
OPRK1 P41145 1/20 0.36
OPRL1 P41146 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LIPG Q9Y5X9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14361695 1.00 MMP2 (0.40) MMP2MMP9MMP3MMP8MMP13
SCHEMBL15578898 1.00 MMP2 (0.40) MMP2MMP9MMP3MMP8MMP13
SCHEMBL14361610 0.94 MMP2 (0.36) MMP2MMP9MMP3MMP8MMP13
SCHEMBL14361783 0.92 MMP2 (0.38) MMP2MMP9MMP3MMP8MMP13
SCHEMBL14361832 0.82 MMP2 (0.39) MMP2MMP9MMP3MMP8MMP13
SCHEMBL14361626 0.82 MMP2 (0.39) MMP2MMP9MMP3MMP8MMP13
SCHEMBL28544166 0.82 MMP2 (0.39) MMP2MMP9MMP3MMP8MMP13
SCHEMBL16252175 0.74 HTT (0.33) MMP2MMP9MMP3MMP8MMP13
SCHEMBL11850394 0.74 MMP2 (0.37) MMP2MMP9MMP3MMP8MMP13
SCHEMBL14361651 0.73 ELANE (0.35) KCNH2SLC9A1GAAMEN1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2895151-A2 MULTI-ENCAPSULATED FORMULATIONS MADE WITH OXIDIZED CELLULOSE Covidien LP (US) 2015-07-22 EP disclosed
US-20140322853-A1 Novel Zwitterionic Polyelectrolytes as Efficient Interface Materials for Application in Optoelectronic Devices Advent Technologies Inc. (US) 2014-10-30 US disclosed
WO-2014043686-A2 MULTI-ENCAPSULATED FORMULATIONS MADE WITH OXIDIZED CELLULOSE CONFLUENT SURGICAL, INC. (US) 2014-03-20 WO disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed