Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923237 | 0.84 | KMT2A (0.53) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL13840614 | 0.84 | KMT2A (0.53) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL11265303 | 0.81 | ADRB2 (0.47) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL5531232 | 0.78 | KMT2A (0.50) | KMT2AMEN1LMNASMN1; SMN2MAOB | |
| SCHEMBL9967892 | 0.78 | GRM5 (0.47) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL11268166 | 0.78 | KDM4E (0.49) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL31413304 | 0.78 | MAOB (0.54) | MAPTKMT2AMEN1LMNACTSV | |
| SCHEMBL220992 | 0.78 | MAOB (0.54) | MAPTKMT2AMEN1LMNACTSV | |
| Hydrochloric Acid SCHEMBL11268346 | 0.78 | KMT2A (0.41) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL3443080 | 0.77 | KMT2A (0.58) | KMT2AMEN1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337272-A | BRONCHODILATOR AGENTS | VALEAS S. R. L. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1982-06-29 | — | — | US | disclosed |
| US-4252824-A | BRONCHODILATOR AGENTS | VALEAS S.R.L., INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1981-02-24 | — | — | US | disclosed |