Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11277277 | 0.99 | ACHE (0.56) | ACHEOPRM1TMEM97SIGMAR1KMT2A | |
| SCHEMBL30423344 | 0.87 | ACHE (0.54) | ACHEKMT2AHDAC1BCHEKDM4E | |
| SCHEMBL4322968 | 0.87 | ACHE (0.54) | ACHEKMT2AHDAC1BCHEKDM4E | |
| Hydrochloric Acid SCHEMBL31650819 | 0.86 | ACHE (0.53) | ACHEKMT2AHDAC1BCHEKDM4E | |
| SCHEMBL11284051 | 0.86 | ACHE (0.57) | ACHEOPRM1TMEM97SIGMAR1BCHE | |
| Hydrochloric Acid SCHEMBL11273784 | 0.85 | ACHE (0.56) | ACHEOPRM1TMEM97SIGMAR1BCHE | |
| Hydrochloric Acid SCHEMBL11277173 | 0.83 | ACHE (0.54) | ACHEOPRM1TMEM97SIGMAR1KMT2A | |
| SCHEMBL11286397 | 0.82 | ACHE (0.50) | ACHETMEM97SIGMAR1KMT2AHDAC1 | |
| SCHEMBL17688511 | 0.80 | ACHE (0.52) | ACHEKMT2ABCHEKDM4EALDH1A1 | |
| SCHEMBL13889650 | 0.79 | KMT2A (0.55) | ACHEKMT2ABCHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |