Nitric Acid

Nitric Acid

SCHEMBL11271447

Clc1ccc(CCC2(Cn3ccnc3)SCCCS2)cc1.O=[N+]([O-])O

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ERG11

The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.47
HMOX1 P09601 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11256591 0.92 HMOX1 (0.54) HMOX1
SCHEMBL10247468 0.87 HMOX1 (0.56) HMOX1
Hydrochloric Acid SCHEMBL410505 0.86 HMOX1 (0.56) HMOX1
SCHEMBL11255636 0.85 HMOX1 (0.49) HMOX1
Nitric Acid SCHEMBL11259601 0.84 HMOX1 (0.51) L3MBTL1HMOX1
Acetic Acid SCHEMBL11261784 0.84 HMOX1 (0.54) HMOX1
Nitric Acid SCHEMBL11267190 0.82 HMOX1 (0.46) L3MBTL1HMOX1
SCHEMBL11256551 0.82 CYP2A6 (0.49) HMOX1
SCHEMBL11261667 0.80 HMOX1 (0.60) HMOX1
SCHEMBL11272917 0.80 HMOX1 (0.51) HMOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359475-A SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS SYNTEX (U.S.A.) INC. (US) 1982-11-16 US disclosed