Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262436 | 0.79 | TSHR (0.47) | TSHRRORCGABRA1GABRB2USP2 | |
| SCHEMBL21767240 | 0.74 | TSHR (0.54) | TSHRRORCGABRA1GABRB2USP2 | |
| SCHEMBL10997664 | 0.73 | TSHR (0.53) | TSHRRORCGABRA1GABRB2USP2 | |
| SCHEMBL11682514 | 0.73 | TSHR (0.50) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL2382143 | 0.72 | TSHR (0.57) | TSHRRORCGABRA1GABRB2USP2 | |
| SCHEMBL9643710 | 0.72 | TSHR (0.47) | TSHRRORCGABRA1GABRB2USP2 | |
| SCHEMBL561299 | 0.71 | TSHR (0.68) | TSHRRORCGABRA1GABRB2USP2 | |
| SCHEMBL202738 | 0.71 | TSHR (0.68) | TSHRRORCGABRA1GABRB2USP2 | |
| SCHEMBL560318 | 0.71 | TSHR (0.68) | TSHRRORCGABRA1GABRB2USP2 | |
| SCHEMBL560346 | 0.71 | TSHR (0.68) | TSHRRORCGABRA1GABRB2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314962-A | DIHYDROXYBENZENE OR BISPHENOL CHAIN EXTENDERS | ETHYL CORPORATION (US) | 1982-02-09 | — | — | US | disclosed |