Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 13/20 | 0.59 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940814 | 1.00 | ACE (0.59) | ACEFFAR2 | |
| SCHEMBL11271681 | 1.00 | ACE (0.59) | ACEFFAR2 | |
| SCHEMBL11271666 | 1.00 | ACE (0.59) | ACEFFAR2 | |
| SCHEMBL10943437 | 0.90 | ACE (0.54) | ACE | |
| SCHEMBL11281944 | 0.90 | ACE (0.54) | ACE | |
| SCHEMBL11274594 | 0.90 | ACE (0.54) | ACE | |
| SCHEMBL11281946 | 0.90 | ACE (0.54) | ACE | |
| SCHEMBL10943539 | 0.86 | ACE (0.46) | ACE | |
| SCHEMBL10730793 | 0.85 | ACE (0.53) | ACEFFAR2 | |
| SCHEMBL11006854 | 0.83 | ACE (0.71) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059966-A1 | Substituted thiazolidine carboxylic acid analogs and derivatives as antihypertensives | MERCK & CO. INC. (US) | 1982-09-15 | — | — | EP | claimed |