Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL11271702

CC(C)(C)N(O)C(=O)c1ccccc1.O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F.[Pd+2]

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
CES1 P23141 1/20 0.43
MLYCD O95822 2/20 0.42
NR1H3 Q13133 2/20 0.39
NR1H2 P55055 1/20 0.39
RECQL P46063 1/20 0.39
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
RORC P51449 1/20 0.37
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C19 P33261 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11263006 0.88 POLB (0.47) POLBCES1RECQLCYP3A4CYP2C9
SCHEMBL3280418 0.86 POLB (0.55) POLBCES1RECQLCYP3A4CYP2C9
SCHEMBL11262719 0.84 POLB (0.53) POLBCES1RECQLCYP3A4CYP2C9
Trifluoroacetic Acid SCHEMBL11271706 0.84 POLB (0.44) POLBCES1MLYCDNR1H3NR1H2
SCHEMBL3278222 0.76 POLB (0.41) POLBMLYCDSMN1; SMN2
SCHEMBL11256613 0.75 MAPT (0.54) POLBSMN1; SMN2MAPT
SCHEMBL3285839 0.73 CYP3A4 (0.53) POLBCYP3A4CYP2C9MEN1KMT2A
Acetic Acid SCHEMBL11270809 0.71 POLB (0.47) POLBCES1RECQLCYP3A4CYP2C9
Benzoic Acid SCHEMBL28286805 0.71 TSHR (0.61) CES1CYP2C9CA2CA4
SCHEMBL9504787 0.70 ALOX5 (0.50) POLBMLYCDMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4365082-A CATALYTIC OXIDATION, ESTERIFICATION INSTITUT FRANCAIS DU PETROLE (FR) 1982-12-21 US disclosed