Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4249807 | 0.92 | KMT2A (0.53) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL1610957 | 0.83 | KMT2A (0.55) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL21088415 | 0.82 | SLC6A4 (0.49) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL12320666 | 0.81 | KMT2A (0.53) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL22261511 | 0.81 | ALDH1A1 (0.53) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL20235825 | 0.80 | NR4A2 (0.60) | KMT2AMEN1MAPTKDM4ENPC1 | |
| SCHEMBL20850165 | 0.80 | MAPT (0.53) | KMT2AMEN1MAPTKDM4ENPC1 | |
| SCHEMBL7130530 | 0.80 | SLC6A4 (0.47) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL12922048 | 0.80 | CYP46A1 (0.57) | KMT2AMEN1MAPTKDM4ETSHR | |
| SCHEMBL28416610 | 0.80 | ALDH1A1 (0.44) | KMT2AMEN1MAPTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330650-A | HAVING MAGNESIUM COMPONENTS, TITANIUM COMPONENTS, ORGANOALUMINUM COMPONENTS AND HETEROCYCLIC CARBOXYLIC ESTER ELECTRON DONOR COMPONENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-05-18 | — | — | US | disclosed |
| US-4255280-A | ORGANOMAGNESIUM, CHLOROSILANE, TITANIUM, ORGANOMETALLIC AND HETEROCYCLIC ESTER COMPONENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-03-10 | — | — | US | disclosed |