Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA4 | P22748 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155993 | 0.98 | TTR (0.41) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11155862 | 0.97 | TTR (0.41) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11153159 | 0.85 | TTR (0.44) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11259309 | 0.85 | TTR (0.43) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11272013 | 0.82 | TTR (0.41) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11178276 | 0.82 | TTR (0.48) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11263651 | 0.82 | LMNA (0.43) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11259678 | 0.82 | TTR (0.46) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11155990 | 0.81 | TTR (0.40) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11171362 | 0.81 | TTR (0.44) | TTRCYP2C9USP2LMNATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |