Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12231761 | 0.71 | CRBN (0.36) | — | |
| SCHEMBL22018249 | 0.70 | MEN1 (0.32) | MEN1POLBKMT2A | |
| SCHEMBL12781627 | 0.67 | CRBN (0.36) | POLB | |
| SCHEMBL12781625 | 0.64 | PDE7A (0.33) | POLB | |
| SCHEMBL11271914 | 0.64 | PDE7A (0.35) | — | |
| SCHEMBL573862 | 0.61 | CRBN (0.37) | — | |
| SCHEMBL2706506 | 0.61 | CRBN (0.40) | — | |
| SCHEMBL542497 | 0.61 | PDE7A (0.47) | — | |
| SCHEMBL22018246 | 0.61 | LMNA (0.33) | — | |
| SCHEMBL630549 | 0.61 | CRBN (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320135-A | HORMONE INHIBITORS, ANTIDIABETIC AGENTS, TREATMENT OF MICROANGIOPATHY | SANDOZ, INC. (US) | 1982-03-16 | — | — | US | claimed |