Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.48 |
| ▸ | FYN | P06241 | 3/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.48 |
| ▸ | TACR2 | P21452 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285364 | 0.93 | CYP2C9 (0.52) | IDO1CYP19A1CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL11280142 | 0.93 | IDO1 (0.56) | IDO1CYP19A1CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL11272390 | 0.89 | IDO1 (0.53) | IDO1CYP19A1CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL11275285 | 0.87 | IDO1 (0.45) | IDO1CYP19A1CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL11272425 | 0.87 | ALDH1A1 (0.53) | IDO1CYP19A1CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL11278619 | 0.87 | ALDH1A1 (0.53) | IDO1CYP19A1CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL11272865 | 0.85 | CYP2C9 (0.55) | IDO1CYP19A1CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL11269197 | 0.84 | CYP2C9 (0.54) | IDO1CYP19A1CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL11273980 | 0.84 | CYP11B1 (0.47) | IDO1CYP19A1CYP11B1CYP11B2TDP1 | |
| SCHEMBL11281976 | 0.84 | IDO1 (0.57) | IDO1CYP19A1CYP2C9CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064244-A1 | Spermicidal 1-bis(arylalkyl)alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-11-10 | — | — | EP | disclosed |