Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280420 | 0.88 | TAAR1 (0.44) | TAAR1CYP2D6TSHRLMNAGLA | |
| SCHEMBL570036 | 0.81 | TAAR1 (0.69) | TAAR1CYP2D6TSHRLMNAGLA | |
| Hydrochloric Acid SCHEMBL1846181 | 0.80 | TAAR1 (0.67) | TAAR1CYP2D6TSHRLMNAGLA | |
| SCHEMBL15121693 | 0.78 | TAAR1 (0.65) | TAAR1CYP2D6TSHRLMNAGLA | |
| SCHEMBL8958092 | 0.78 | TAAR1 (0.65) | TAAR1CYP2D6TSHRLMNAGLA | |
| SCHEMBL2942858 | 0.77 | TAAR1 (0.62) | TAAR1CYP2D6TSHRLMNAGLA | |
| Hydrochloric Acid SCHEMBL3645890 | 0.77 | TAAR1 (0.62) | TAAR1CYP2D6TSHRLMNAGLA | |
| SCHEMBL14003640 | 0.76 | TBXAS1 (0.47) | TAAR1SMN1; SMN2TBXAS1HTR1ATERT | |
| SCHEMBL7607964 | 0.74 | TAAR1 (0.42) | TAAR1CYP2D6TSHRLMNAGLA | |
| SCHEMBL30679671 | 0.73 | TAAR1 (0.57) | TAAR1CYP2D6TSHRLMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064244-A1 | Spermicidal 1-bis(arylalkyl)alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-11-10 | — | — | EP | disclosed |