Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266149 | 0.81 | HIF1A (0.44) | CYP2C19HIF1AMAPTALDH1A1CHRM2 | |
| SCHEMBL8034194 | 0.78 | HIF1A (0.59) | CYP2C19HIF1AMAPTALDH1A1CHRM2 | |
| SCHEMBL6823582 | 0.77 | CYP2C19 (0.49) | CYP2C19HIF1AALDH1A1CHRM3CYP2D6 | |
| SCHEMBL7057674 | 0.76 | MAPK1 (0.47) | CYP2C19HIF1AMAPTALDH1A1CHRM2 | |
| SCHEMBL25338001 | 0.75 | CYP2C19 (0.44) | CYP2C19HIF1AMAPTALDH1A1CHRM2 | |
| SCHEMBL7055626 | 0.75 | MAPK1 (0.46) | CYP2C19HIF1AMAPTALDH1A1CHRM2 | |
| SCHEMBL599044 | 0.73 | CYP2C19 (0.54) | CYP2C19HIF1AMAPTALDH1A1KMT2A | |
| SCHEMBL10808021 | 0.73 | CYP2C19 (0.54) | CYP2C19HIF1AMAPTALDH1A1KMT2A | |
| SCHEMBL25337119 | 0.73 | ALDH1A1 (0.45) | CYP2C19HIF1AALDH1A1KMT2AMEN1 | |
| SCHEMBL3742631 | 0.73 | CYP2C19 (0.81) | CYP2C19HIF1AMAPTALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361688-A | CATALYSTS FOR ADDITION POLYMERIZATION | ARGUS CHEMICAL CORPORATION (US) | 1982-11-30 | — | — | US | claimed |
| US-4285877-A | SOLID FREE RADICAL CATALYSTS; STORAGE STABILITY | ARGUS CHEMICAL CORPORATION (US) | 1981-08-25 | — | — | US | claimed |