Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11011356 | 0.85 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL11839696 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL21682356 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL2641242 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL2264417 | 0.76 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL15284855 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL24178952 | 0.74 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL8786940 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL16303102 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL14252722 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334073-A | BASIC CATALYSTS, DEACETYLATION, ESTERIFICATION | BAYER AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | claimed |