Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272377 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPK1HPGDALOX15HSD17B10 | |
| SCHEMBL11264392 | 0.84 | CYP1A2 (0.39) | ALDH1A1MAPK1HPGDALOX15HSD17B10 | |
| SCHEMBL11264388 | 0.84 | CYP1A2 (0.39) | ALDH1A1MAPK1HPGDALOX15HSD17B10 | |
| SCHEMBL11251471 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MAPK1HPGDALOX15HSD17B10 | |
| SCHEMBL11250168 | 0.83 | SMN1; SMN2 (0.40) | ALDH1A1MAPK1HPGDALOX15HSD17B10 | |
| SCHEMBL11250171 | 0.83 | SMN1; SMN2 (0.40) | ALDH1A1MAPK1HPGDALOX15HSD17B10 | |
| SCHEMBL11268627 | 0.80 | KDM4E (0.42) | ALDH1A1MAPK1HPGDALOX15HSD17B10 | |
| SCHEMBL11268619 | 0.80 | KDM4E (0.42) | ALDH1A1MAPK1HPGDALOX15HSD17B10 | |
| SCHEMBL11257109 | 0.79 | KDM4E (0.39) | ALDH1A1MAPK1HPGDALOX15HSD17B10 | |
| SCHEMBL11257108 | 0.79 | KDM4E (0.39) | ALDH1A1MAPK1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349674-A | Quinoalinyl esters of carbamimidothioic acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-14 | — | — | US | claimed |