Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331222 | 0.84 | ATM (0.71) | ATMALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28775954 | 0.82 | ATM (0.69) | ATMALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3211700 | 0.82 | ATM (0.69) | ATMALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1419333 | 0.82 | ATM (0.69) | ATMALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28802548 | 0.82 | ATM (0.69) | ATMALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL25240419 | 0.82 | ATM (0.69) | ATMALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6052462 | 0.82 | ATM (0.69) | ATMALDH1A1KMT2APOLBCYP1A2 | |
| SCHEMBL6634976 | 0.82 | ATM (0.69) | ATMALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL2558718 | 0.81 | ATM (0.68) | ATMALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL10619729 | 0.81 | ATM (0.67) | ATMALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050049285-A1 | Dichloropyridyl methyl cyanamidines | BAYER CROPSCIENCE AG (DE) | 2005-03-03 | — | — | US | claimed |
| US-4380629-A | Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime | MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) | 1983-04-19 | — | — | US | claimed |
| US-4314058-A | Indolins styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1982-02-02 | — | — | US | claimed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | claimed |
| JP-55076813-A | — | — | None | — | — | JP | disclosed |
| US-20250066347-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | MEDIFIC, INC. (KR) | 2025-02-27 | — | — | US | disclosed |
| EP-4455143-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | Medific, Inc. (KR) | 2024-10-30 | — | — | EP | disclosed |
| CN-118591539-A | Substituted thiazolidinedione derivative compounds and pharmaceutical composition for preventing or treating cancer comprising the same | (株)美迪菲 | 2024-09-03 | — | — | CN | disclosed |
| EP-3615514-B1 | PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS INC (US) | 2023-11-22 | — | — | EP | disclosed |
| EP-3615514-B1 | PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS INC (US) | 2023-11-22 | — | — | EP | disclosed |
| CN-110914242-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-07-25 | — | — | CN | disclosed |
| WO-2023121184-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |
| US-4380629-A | Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime | MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) | 1983-04-19 | — | — | US | disclosed |
| US-4340624-A | STYRYL-LIKE COMPOUNDS | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1982-07-20 | — | — | US | disclosed |
| US-4314058-A | Indolins styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4234677-A | ANTIHALATION AGENTS, MORDANTS, AND FILTERS | CIBA-GEIGY AG (CH) | 1980-11-18 | — | — | US | disclosed |
| JP-S5576813-A | PREPARATION OF PERFUME COMPOSITION | SHIONO KORYO KK | 1980-06-10 | — | — | JP | disclosed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4139274-A | Apparatus for changing color | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-02-13 | — | — | US | disclosed |
| US-4003633-A | Color display device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066347-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | SREBF1, SREBF2, SP1 | ATM 914/4885ALDH1A1 1168/4885KMT2A 2182/4885 |
| US-20050049285-A1 | Dichloropyridyl methyl cyanamidines | MRPL21, DDT, FBL | ATM 1193/4885ALDH1A1 2077/4885KMT2A 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.