Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.54 |
| ▸ | EBP | Q15125 | 2/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11272832 | 0.99 | HRH3 (0.61) | HRH3SIGMAR1EBPTMEM97ACHE | |
| Hydrochloric Acid SCHEMBL11273651 | 0.99 | HRH3 (0.61) | HRH3SIGMAR1EBPTMEM97ACHE | |
| SCHEMBL11265275 | 0.98 | HRH3 (0.65) | HRH3SIGMAR1EBPTMEM97ACHE | |
| Hydrochloric Acid SCHEMBL11283727 | 0.97 | HRH3 (0.63) | HRH3SIGMAR1EBPTMEM97ACHE | |
| Hydrochloric Acid SCHEMBL11276469 | 0.85 | SIGMAR1 (0.54) | HRH3SIGMAR1EBPTMEM97 | |
| SCHEMBL11274496 | 0.84 | HRH3 (0.61) | HRH3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11283706 | 0.84 | HRH3 (0.71) | HRH3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11282997 | 0.82 | MEN1 (0.56) | ACHE | |
| SCHEMBL11284196 | 0.80 | HRH3 (0.69) | HRH3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11284452 | 0.80 | HRH3 (0.56) | HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |