Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273163 | 1.00 | LOXL2 (0.46) | LOXL2KMT2AMEN1TSHRCYP2C19 | |
| SCHEMBL28780363 | 0.81 | LOXL2 (0.42) | LOXL2KMT2AMEN1TSHRCYP2C19 | |
| SCHEMBL28136599 | 0.80 | SMN1; SMN2 (0.58) | TSHRCYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6981342 | 0.80 | SMN1; SMN2 (0.58) | TSHRCYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11265928 | 0.80 | SMN1; SMN2 (0.58) | TSHRCYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5171078 | 0.80 | EPHX1 (0.44) | KMT2AMEN1CYP2C19CYP1A2SMN1; SMN2 | |
| SCHEMBL3413763 | 0.80 | EPHX1 (0.44) | KMT2AMEN1CYP2C19CYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17262536 | 0.79 | SMN1; SMN2 (0.56) | TSHRCYP1A2NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7744795 | 0.78 | CYP2C19 (0.46) | LOXL2TSHRCYP2C19CYP1A2NPC1 | |
| Hydrochloric Acid SCHEMBL7744797 | 0.78 | CYP2C19 (0.46) | LOXL2TSHRCYP2C19CYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339589-A | Preparation of 4-substituted oxazolidin-5-ones | BASF AKTIENGESELLSCHAFT (DE) | 1982-07-13 | — | — | US | disclosed |
| US-4264771-A | Alkylation of substituted oxazolinone-(5) compounds | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |