Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381793 | 0.87 | TSHR (0.32) | TSHR | |
| SCHEMBL11257583 | 0.83 | TSHR (0.44) | TSHRALDH1A1USP2TP53SMN1; SMN2 | |
| SCHEMBL11269468 | 0.79 | TSHR (0.37) | TSHRALDH1A1USP2TP53SMN1; SMN2 | |
| SCHEMBL27934655 | 0.78 | ALDH1A1 (0.41) | TSHRALDH1A1USP2TP53SMN1; SMN2 | |
| SCHEMBL3838166 | 0.77 | ALDH1A1 (0.40) | TSHRALDH1A1USP2HSD17B10MEN1 | |
| SCHEMBL9173496 | 0.76 | ALDH1A1 (0.40) | TSHRALDH1A1USP2TP53SMN1; SMN2 | |
| SCHEMBL11619115 | 0.76 | ALDH1A1 (0.39) | TSHRALDH1A1USP2TP53SMN1; SMN2 | |
| SCHEMBL9174745 | 0.75 | ALDH1A1 (0.39) | TSHRALDH1A1USP2TP53SMN1; SMN2 | |
| SCHEMBL11132401 | 0.75 | ALDH1A1 (0.40) | TSHRALDH1A1USP2TP53SMN1; SMN2 | |
| SCHEMBL11622404 | 0.73 | ALDH1A1 (0.42) | TSHRALDH1A1USP2TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043348-A1 | Imidazolidine-2,4-dione derivatives, process for their preparation and their microbicidal application | CIBA-GEIGY AG (CH) | 1982-01-06 | — | — | EP | claimed |