Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | ACP1 | P24666 | 4/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ILK | Q13418 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831519 | 0.80 | HRH3 (0.55) | ACP1HRH3 | |
| SCHEMBL10831606 | 0.80 | HRH3 (0.55) | ACP1HRH3 | |
| SCHEMBL10831339 | 0.79 | HRH3 (0.53) | HTR2AACP1HRH3HTR1A | |
| SCHEMBL11206157 | 0.79 | HTR2A (0.49) | SLC6A2HTR2AHTR2CHTR6HTR1A | |
| SCHEMBL10831306 | 0.76 | HRH3 (0.54) | HTR2AACP1HRH3HTR1A | |
| SCHEMBL11147779 | 0.72 | KAT2B (0.54) | ACP1HRH3ILK | |
| SCHEMBL10831286 | 0.72 | KAT2B (0.54) | ACP1HRH3ILK | |
| SCHEMBL10369412 | 0.71 | HRH3 (0.53) | ACP1HRH3 | |
| SCHEMBL10371164 | 0.71 | HRH3 (0.53) | ACP1HRH3 | |
| SCHEMBL10368034 | 0.71 | HRH3 (0.45) | ACP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049779-A1 | 3-Aminoindazole derivatives and process for preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-04-21 | — | — | EP | disclosed |