Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977049 | 0.91 | ALDH1A1 (0.47) | MAPTGAAALDH1A1KDM4EKMT2A | |
| SCHEMBL3977290 | 0.77 | MAPT (0.50) | MAPTGAAALDH1A1KDM4EKMT2A | |
| SCHEMBL3976144 | 0.75 | PPARG (0.50) | MAPTKMT2AMEN1MAOB | |
| SCHEMBL3982536 | 0.75 | TSHR (0.47) | MAPTGAAALDH1A1KDM4EKMT2A | |
| SCHEMBL27569291 | 0.75 | ALDH1A1 (0.57) | MAPTGAAALDH1A1KDM4EKMT2A | |
| SCHEMBL4282758 | 0.74 | CDC7 (0.48) | MAPTGAAALDH1A1KDM4EKMT2A | |
| SCHEMBL3977434 | 0.74 | KMT2A (0.47) | MAPTGAAALDH1A1KDM4EKMT2A | |
| SCHEMBL3979225 | 0.74 | MAPT (0.41) | MAPTGAAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL3978078 | 0.73 | ALDH1A1 (0.51) | MAPTGAAALDH1A1KDM4EKMT2A | |
| SCHEMBL3981475 | 0.73 | GAA (0.45) | MAPTGAAALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |