⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15121222 | 0.83 | LMNA (0.36) | — | |
| SCHEMBL16187939 | 0.77 | PIK3CD (0.32) | — | |
| SCHEMBL6935604 | 0.77 | PIK3CD (0.32) | — | |
| SCHEMBL16187959 | 0.77 | PIK3CD (0.32) | — | |
| SCHEMBL13184613 | 0.74 | — | — | |
| SCHEMBL15147710 | 0.72 | — | — | |
| SCHEMBL6933473 | 0.70 | — | — | |
| SCHEMBL2503689 | 0.69 | — | — | |
| SCHEMBL2459380 | 0.69 | MAPK1 (0.40) | — | |
| SCHEMBL25070434 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230256098-A1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | BANK OF AMERICA, N.A. | 2023-08-17 | — | — | US | disclosed |
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-20170233734-A1 | NUCLEIC ACID LIPID PARTICLE FORMULATIONS | ALNYLAM PHARMACEUTICALS INC (US) | 2017-08-17 | — | — | US | disclosed |
| US-9687448-B2 | Nucleic acid lipid particle formulations | ALNYLAM PHARMACEUTICALS, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20150306039-A1 | IMPROVED NUCLEIC ACID LIPID PARTICLE FORMULATIONS | BANK OF AMERICA, N.A. | 2015-10-29 | — | — | US | disclosed |
| US-20150273068-A1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | BANK OF AMERICA, N.A. | 2015-10-01 | — | — | US | disclosed |
| US-9061063-B2 | Biodegradable lipids for the delivery of active agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-20130195920-A1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-4329439-A | AN ORGANOLITHIUM COMPONENT, AND AN AMINO-ACETAL COMPONENT OF THE CATALYST | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4280927-A | A CHELATE OF HYDROCARBYL LITHIUM AND A DIALKYLAMINOALDEHYDE DIALKYL ACETAL | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-07-28 | — | — | US | disclosed |