Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264746 | 0.83 | KMT2A (0.54) | MEN1KMT2AHPGDNPSR1NPC1 | |
| SCHEMBL11258765 | 0.83 | KMT2A (0.47) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL11262889 | 0.82 | MEN1 (0.46) | MEN1KMT2ANPSR1HDAC1HDAC6 | |
| SCHEMBL11263216 | 0.82 | MEN1 (0.46) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL11265941 | 0.80 | MEN1 (0.54) | MEN1TP53KMT2ANPSR1NPC1 | |
| SCHEMBL10090175 | 0.80 | LMNA (0.63) | TP53HPGDNPSR1NPC1RAB9A | |
| SCHEMBL11275088 | 0.79 | EPHX1 (0.64) | MEN1KMT2AHPGDNPSR1ALDH1A1 | |
| SCHEMBL11270939 | 0.78 | ABAT (0.56) | MEN1TP53KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL11270488 | 0.78 | USP2 (0.55) | MEN1KMT2AHPGDNPSR1RAB9A | |
| SCHEMBL10090167 | 0.77 | MEN1 (0.62) | MEN1TP53KMT2AHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350700-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1982-09-21 | — | — | US | disclosed |
| US-4287207-A | USED AS AN ANALGESIC, ANTIPYRETIC OR ANTIINFLAMMATORY AGENT | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-09-01 | — | — | US | disclosed |