Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 10/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11280052 | 0.98 | NISCH (0.56) | NISCHGAATSHRNOS3NOS1 | |
| SCHEMBL11285269 | 0.95 | NISCH (0.51) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL80782 | 0.89 | NISCH (0.62) | NISCH | |
| Bromide SCHEMBL82800 | 0.87 | NISCH (0.61) | NISCH | |
| Hydrochloric Acid SCHEMBL11299051 | 0.86 | NISCH (0.59) | NISCH | |
| SCHEMBL11284192 | 0.79 | NISCH (0.46) | NISCHGAATSHRNOS3NOS1 | |
| SCHEMBL13830922 | 0.79 | NISCH (0.58) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL6746742 | 0.79 | NISCH (0.80) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL4298620 | 0.79 | NISCH (0.58) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL14046102 | 0.79 | NISCH (0.58) | NISCHGAATSHRTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046446-A1 | Polyazaheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1982-02-24 | — | — | EP | disclosed |