Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 9/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 4/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300573 | 0.90 | NISCH (0.52) | NISCH | |
| SCHEMBL11273702 | 0.79 | NISCH (0.58) | NISCHGAATSHRTOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL11280052 | 0.78 | NISCH (0.56) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL11285269 | 0.75 | NISCH (0.51) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL5141529 | 0.69 | NISCH (0.80) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL28428254 | 0.69 | NISCH (0.60) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL4035056 | 0.68 | NISCH (0.68) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL80782 | 0.68 | NISCH (0.62) | NISCH | |
| SCHEMBL9114689 | 0.68 | NISCH (0.57) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL13327264 | 0.68 | NISCH (0.81) | NISCHGAATSHRTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046446-A1 | Polyazaheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1982-02-24 | — | — | EP | disclosed |