Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709716 | 0.83 | PLD1 (0.60) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL2244221 | 0.83 | PLD1 (0.60) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL31745447 | 0.83 | PLD1 (0.60) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL234735 | 0.83 | PLD1 (0.60) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| Bromide SCHEMBL4002504 | 0.81 | PLD1 (0.58) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| Bromide SCHEMBL4002506 | 0.81 | PLD1 (0.58) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL7801440 | 0.81 | PLD1 (0.58) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL31046391 | 0.81 | PLD1 (0.58) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL3183212 | 0.81 | PLD1 (0.54) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL16474292 | 0.77 | PLD1 (0.51) | PLD1HSD17B10SMN1; SMN2GRIN2BGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |