Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029438 | 0.86 | TP53 (0.33) | PARP10 | |
| SCHEMBL32688392 | 0.84 | — | — | |
| SCHEMBL11283937 | 0.80 | — | — | |
| SCHEMBL17199492 | 0.76 | PDE4A (0.31) | — | |
| SCHEMBL14804671 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL21318822 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL2116014 | 0.75 | PTGS1 (0.34) | — | |
| SCHEMBL21318913 | 0.74 | — | — | |
| SCHEMBL6051489 | 0.74 | GAA (0.36) | — | |
| SCHEMBL11274651 | 0.73 | MCHR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131910-A1 | USE OF A L,3J5-TRIAZIN-2-YL PHOSPHORAMIDATE COMPOUND IN THE SYNTHESIS OF SOFOSBUVIR | Zentiva K.S. (CZ) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015158317-A1 | USE OF A L,3J5-TRIAZIN-2-YL PHOSPHORAMIDATE COMPOUND IN THE SYNTHESIS OF SOFOSBUVIR | ZENTIVA, K.S. (CZ) | 2015-10-22 | — | — | WO | disclosed |
| WO-2015158317-A1 | USE OF A L,3J5-TRIAZIN-2-YL PHOSPHORAMIDATE COMPOUND IN THE SYNTHESIS OF SOFOSBUVIR | ZENTIVA, K.S. (CZ) | 2015-10-22 | — | — | WO | disclosed |
| US-4320126-A | INSECTICIDES, MITICIDES, NEMATOCIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-16 | — | — | US | disclosed |