Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273872 | 0.84 | PTGER4 (0.41) | HMGCRHSD17B10PTGER4AGTR1AGTR2 | |
| SCHEMBL11267818 | 0.84 | HPGD (0.49) | RHEBHMGCRHSD17B10HTTLMNA | |
| SCHEMBL11211254 | 0.84 | NPSR1 (0.40) | RHEBRAB9ASMN1; SMN2HSD17B10HTT | |
| SCHEMBL11274681 | 0.82 | RHEB (0.47) | RHEBNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL11273342 | 0.77 | NPSR1 (0.38) | RHEBTP53SMN1; SMN2HTTAGTR1 | |
| SCHEMBL11498688 | 0.75 | NPSR1 (0.37) | RHEBHTTNPSR1MAPT | |
| SCHEMBL11271209 | 0.74 | GAA (0.46) | HTTTSHR | |
| SCHEMBL11269144 | 0.73 | NPSR1 (0.41) | RHEBNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL11276318 | 0.72 | MEN1 (0.38) | NPC1RAB9AHTTLMNAMAPK1 | |
| SCHEMBL11267704 | 0.71 | PPARG (0.38) | NPC1RAB9AHTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |