SCHEMBL11274283

SCHEMBL11274283

Clc1ccc(CCC(CCc2ccccc2)Cn2ccnc2)c(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 6/20 0.54
CYP2C9 P11712 5/20 0.51
NR1I2 O75469 4/20 0.51
PGR P06401 4/20 0.51
ADORA3 P0DMS8 4/20 0.51
ADRA2B P18089 4/20 0.51
CHRM3 P20309 4/20 0.51
OPRK1 P41145 4/20 0.51
KCNH2 Q12809 4/20 0.51
CYP19A1 P11511 3/20 0.51
NR3C1 P04150 3/20 0.51
CYP1A2 P05177 3/20 0.51
CYP3A4 P08684 3/20 0.51
CYP2D6 P10635 3/20 0.51
CYP2C19 P33261 3/20 0.51
SLC6A3 Q01959 3/20 0.51
CNR1 P21554 3/20 0.51
SLC6A2 P23975 3/20 0.51
SLC6A4 P31645 3/20 0.51
DRD3 P35462 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11272865 0.93 CYP2C9 (0.55) IDO1CYP2C9NR1I2PGRADORA3
SCHEMBL11283227 0.93 CYP2C9 (0.53) IDO1CYP2C9NR1I2PGRADORA3
SCHEMBL11272390 0.92 IDO1 (0.53) IDO1CYP2C9NR1I2PGRADORA3
SCHEMBL11278579 0.89 CYP1A2 (0.52) IDO1CYP2C9NR1I2PGRADORA3
SCHEMBL11280142 0.89 IDO1 (0.56) IDO1CYP2C9NR1I2PGRADORA3
SCHEMBL11271894 0.89 IDO1 (0.59) IDO1CYP2C9NR1I2PGRADORA3
SCHEMBL11286265 0.88 CYP2C9 (0.50) IDO1CYP2C9NR1I2PGRADORA3
SCHEMBL11274465 0.87 CYP1A2 (0.61) IDO1CYP2C9NR1I2PGRADORA3
SCHEMBL11272141 0.87 CYP1A2 (0.60) IDO1CYP2C9NR1I2PGRADORA3
Hydrochloric Acid SCHEMBL11273552 0.86 CYP1A2 (0.59) IDO1CYP2C9NR1I2PGRADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0064244-A1 Spermicidal 1-bis(arylalkyl)alkylimidazoles SYNTEX (U.S.A.) INC. (US) 1982-11-10 EP disclosed