Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11275024 | 0.98 | HTR2C (0.36) | HTR2CHTR2AHTR2BGAAADRB1 | |
| SCHEMBL11262097 | 0.89 | HTR2C (0.39) | HTR2CHTR2AHTR2BGAAADRB1 | |
| Hydrochloric Acid SCHEMBL11269902 | 0.88 | HTR2C (0.38) | HTR2CHTR2AHTR2BGAAADRB1 | |
| SCHEMBL11269627 | 0.83 | HTR2C (0.36) | HTR2CHTR2AHTR2BCHRNB2CHRNA4 | |
| SCHEMBL11272867 | 0.78 | — | — | |
| SCHEMBL11273290 | 0.78 | MEN1 (0.37) | HTR2CHTR2AHTR2BGAAALDH1A1 | |
| SCHEMBL11260229 | 0.77 | HTR2A (0.39) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL11270222 | 0.76 | HTR2A (0.38) | HTR2CHTR2AHTR2BGAAADRA2A | |
| SCHEMBL11275332 | 0.75 | MAPT (0.36) | HTR2CGAAALDH1A1MAPTHPGD | |
| SCHEMBL11280825 | 0.74 | HTR2C (0.38) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | claimed |
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |