Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281614 | 0.88 | ALDH1A1 (0.42) | POLBHPGDALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL10572689 | 0.82 | POLB (0.55) | POLBHSD17B10STAT3HPGDAVPR2 | |
| SCHEMBL10569932 | 0.79 | POLB (0.49) | POLBHSD17B10STAT3HPGDAVPR2 | |
| SCHEMBL10573458 | 0.79 | POLB (0.51) | POLBHSD17B10STAT3AVPR2AVPR1A | |
| SCHEMBL10652857 | 0.79 | POLB (0.51) | POLBHSD17B10STAT3HPGDAVPR2 | |
| SCHEMBL10570434 | 0.78 | POLB (0.50) | POLBHSD17B10STAT3HPGDALDH1A1 | |
| SCHEMBL10570618 | 0.78 | POLB (0.48) | POLBHSD17B10STAT3HPGDAVPR2 | |
| Oxalic Acid SCHEMBL10574298 | 0.77 | POLB (0.49) | POLBHSD17B10STAT3HPGDAVPR2 | |
| Nicainoprol SCHEMBL1816282 | 0.77 | HSD17B10 (0.49) | POLBHSD17B10STAT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL10570429 | 0.77 | POLB (0.49) | POLBHSD17B10STAT3HPGDAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335123-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |