Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SCN1A | P35498 | 3/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27941514 | 0.89 | PIN1 (0.47) | PIN1MEN1KMT2AATMMAPT | |
| SCHEMBL28987118 | 0.87 | PIN1 (0.41) | PIN1MEN1KMT2AATMMAPT | |
| SCHEMBL5511990 | 0.86 | GAA (0.46) | CYP3A4TSHRCYP2C19SIGMAR1ALDH1A1 | |
| SCHEMBL11291699 | 0.84 | GAA (0.45) | ALDH1A1GAA | |
| SCHEMBL21268865 | 0.84 | GAA (0.45) | CYP3A4TSHRCYP2C19SIGMAR1ALDH1A1 | |
| SCHEMBL11288238 | 0.84 | GAA (0.45) | ALDH1A1GAA | |
| SCHEMBL7102239 | 0.84 | GAA (0.45) | ALDH1A1GAA | |
| SCHEMBL21269704 | 0.84 | GAA (0.45) | CYP3A4TSHRCYP2C19SIGMAR1ALDH1A1 | |
| SCHEMBL21269947 | 0.84 | GAA (0.45) | CYP3A4TSHRCYP2C19SIGMAR1ALDH1A1 | |
| SCHEMBL11294880 | 0.84 | GAA (0.45) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |