SCHEMBL11275191

SCHEMBL11275191

CCCCC1CCC(c2ccc(-c3ccc(OCC(C)CC)cc3)cc2)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.39
CYP2C9 P11712 3/20 0.38
HRH3 Q9Y5N1 3/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
MAPK1 P28482 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
FFAR1 O14842 1/20 0.36
SIGMAR1 Q99720 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP3A4 P08684 1/20 0.35
ESR2 Q92731 1/20 0.34
SPHK1 Q9NYA1 1/20 0.33
CRBN Q96SW2 1/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11284189 0.96 RAB9A (0.38) RAB9ACYP2C9HRH3MAPTMEN1
SCHEMBL11285684 0.95 RAB9A (0.37) RAB9ACYP2C9HRH3MAPTMEN1
SCHEMBL11278902 0.95 RAB9A (0.37) RAB9ACYP2C9HRH3MAPTMEN1
SCHEMBL11283114 0.95 RAB9A (0.37) RAB9ACYP2C9HRH3MAPTMEN1
SCHEMBL11271548 0.95 RAB9A (0.37) RAB9ACYP2C9HRH3MAPTMEN1
SCHEMBL11285915 0.95 RAB9A (0.37) RAB9ACYP2C9HRH3MAPTMEN1
SCHEMBL11288482 0.95 RAB9A (0.37) RAB9ACYP2C9HRH3MAPTMEN1
SCHEMBL11283596 0.95 RAB9A (0.37) RAB9ACYP2C9HRH3MAPTMEN1
SCHEMBL11044470 0.93 RAB9A (0.39) RAB9ACYP2C9HRH3MAPTMEN1
SCHEMBL11280959 0.93 CYP2C9 (0.45) RAB9ACYP2C9HRH3MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022183-B1 DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS MERCK PATENT GmbH (DE) 1982-06-23 EP disclosed
US-4330426-A Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-18 US disclosed
EP-0022183-A2 Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements MERCK PATENT GmbH (DE) 1981-01-14 EP disclosed