SCHEMBL11275353

SCHEMBL11275353

CCOCCO[Si](CCCl)(CCCl)OCCOCC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11278199 0.90 TSHR (0.31) TSHR
SCHEMBL11268859 0.82 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL19356649 0.81 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL11273481 0.78 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL11273350 0.78 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL11268616 0.78 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL11273718 0.78 SMN1; SMN2 (0.37) ALDH1A1TSHR
SCHEMBL11040318 0.78
SCHEMBL19356768 0.77 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL11278238 0.77 ALDH1A1 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4332612-A N-METHYL-2-PYRROLIDONE AND A HALOALKYL SILANE GAF CORPORATION (US) 1982-06-01 US disclosed