Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28529666 | 1.00 | — | — | |
| Bicarbonate SCHEMBL20212138 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL28570300 | 1.00 | — | — | |
| Bicarbonate SCHEMBL176447 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL367726 | 1.00 | — | — | |
| Bicarbonate SCHEMBL22749424 | 1.00 | — | — | |
| Bicarbonate SCHEMBL993052 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL4662241 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL991388 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL2956723 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354341-B1 | METHOD OF PRODUCTION OF PEROVSKITE STRUCTURE CATALYSTS, PEROVSKITE STRUCTURE CATALYSTS AND USE THEREOF FOR HIGH TEMPERATURE DECOMPOSITION OF N2O | USTAV FYZIKALNI CHEMIE J HEYROVSKEHO AV CR V V I (CZ) | 2023-09-20 | — | — | EP | disclosed |
| CN-110997081-B | Surfactant mixtures, compositions comprising them and their use in foam concentrates for fire extinguishing | 化工产品开发公司SEPPIC | 2022-03-15 | — | — | CN | disclosed |
| CN-110249038-B | Novel surfactant mixtures, novel compositions comprising the same and their use in foam concentrates for extinguishing fires | 化工产品开发公司SEPPIC | 2021-11-26 | — | — | CN | disclosed |
| US-20210337786-A1 | COMPOSITION FOR DECONTAMINATING SOLID SURFACES | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2021-11-04 | — | — | US | disclosed |
| US-20210146183-A1 | NEW SURFACTANT MIXTURE, NEW COMPOSITION COMPRISING SAME, AND USE THEREOF IN FOAM LIQUIDS FOR FIGHTING FIRES | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2021-05-20 | — | — | US | disclosed |
| CN-112770630-A | Composition for decontaminating solid surfaces | 化工产品开发公司SEPPIC | 2021-05-07 | — | — | CN | disclosed |
| CN-110997081-A | Novel surfactant mixtures, novel compositions comprising the same and their use in foam concentrates for extinguishing fires | 化工产品开发公司SEPPIC | 2020-04-10 | — | — | CN | disclosed |
| US-20190314660-A1 | NOVEL SURFACTANT MIXTURE, NOVEL COMPOSITION COMPRISING SAME AND USE THEREOF IN FOAM LIQUIDS FOR FIGHTING FIRES | SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2019-10-17 | — | — | US | disclosed |
| EP-3354341-A1 | METHOD OF PRODUCTION OF PEROVSKITE STRUCTURE CATALYSTS, PEROVSKITE STRUCTURE CATALYSTS AND USE THEREOF FOR HIGH TEMPERATURE DECOMPOSITION OF N2O | Ustav Fyzikalni Chemie J. Heyrovskeho AV CR, v.v.i (CZ) | 2018-08-01 | — | — | EP | disclosed |
| EP-0051659-A4 | SYSTEM FOR BICARBONATE DIALYSATE. | BABB ALBERT L (US) | 1982-11-08 | — | — | EP | disclosed |
| EP-0051659-A1 | SYSTEM FOR BICARBONATE DIALYSATE | BABB, Albert L. (US) | 1982-05-19 | — | — | EP | disclosed |
| WO-1981003180-A1 | SYSTEM FOR BICARBONATE DIALYSATE | BABB A | 1981-11-12 | — | — | WO | disclosed |