Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28529666 | 1.00 | — | — | |
| Bicarbonate SCHEMBL20212138 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL28570300 | 1.00 | — | — | |
| Bicarbonate SCHEMBL176447 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL367726 | 1.00 | — | — | |
| Bicarbonate SCHEMBL22749424 | 1.00 | — | — | |
| Bicarbonate SCHEMBL4662241 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL991388 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL2956723 | 1.00 | — | — | |
| Bicarbonate SCHEMBL11275433 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768584-A | Temperature-resistant, corrosion-resistant and leakage-stopping material and preparation method thereof | 南京科赫科技有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-113355927-A | Environment-friendly plant dye for blended material and dyeing process thereof | 浙江超凡制衣有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-111304925-A | Block polyether amino silicone oil softening agent and preparation method thereof | 中山市天信助剂实业有限公司 | 2020-06-19 | — | — | CN | claimed |
| CN-119701972-A | Bio-based fatty acid methyl ester hydrogenation catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119702063-A | Bio-based fatty acid methyl ester hydrogenation catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-116768584-A | Temperature-resistant, corrosion-resistant and leakage-stopping material and preparation method thereof | 南京科赫科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116768584-A | Temperature-resistant, corrosion-resistant and leakage-stopping material and preparation method thereof | 南京科赫科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-111392753-B | Method for separating out sodium bicarbonate from deep carbonation mother liquor | 中国铝业股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-113355927-A | Environment-friendly plant dye for blended material and dyeing process thereof | 浙江超凡制衣有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-111392753-A | Method for separating out sodium bicarbonate from deep carbonation mother liquor | 中国铝业股份有限公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-111304925-A | Block polyether amino silicone oil softening agent and preparation method thereof | 中山市天信助剂实业有限公司 | 2020-06-19 | — | — | CN | disclosed |
| US-20170135363-A1 | METHOD FOR REFINING LIPID PHASES, AND USE | DREI LILIEN PVG GMBH & CO. KG (DE) | 2017-05-18 | — | — | US | disclosed |
| EP-2292701-B2 | Method for improving opacity | OMYA INT AG (CH) | 2017-01-25 | — | — | EP | disclosed |
| US-8821628-B2 | Method for improving opacity | OMYA INTERNATIONAL AG (CH) | 2014-09-02 | — | — | US | disclosed |
| CN-102471607-B | Method for improving opacity | OMYA DEVELOPMENT AG | 2014-04-23 | — | — | CN | disclosed |
| EP-2292701-B1 | Method for improving opacity | OMYA DEVELOPMENT AG (CH) | 2013-09-04 | — | — | EP | disclosed |
| EP-2449035-A1 | METHOD FOR IMPROVING OPACITY | Omya Development AG (CH) | 2012-05-09 | — | — | EP | disclosed |
| US-20120097069-A1 | METHOD FOR IMPROVING OPACITY | OMYA INTERNATIONAL AG (CH) | 2012-04-26 | — | — | US | disclosed |
| EP-2292701-A1 | Method for improving opacity | Omya Development AG (CH) | 2011-03-09 | — | — | EP | disclosed |
| WO-2011001374-A1 | METHOD FOR IMPROVING OPACITY | OMYA DEVELOPMENT AG (CH) | 2011-01-06 | — | — | WO | disclosed |