Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.60 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL20212137 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL15021193 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL176448 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL993053 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL77648 | 1.00 | — | — | |
| Bicarbonate SCHEMBL11693424 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL15021043 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL991389 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL17477711 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL3791433 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354341-B1 | METHOD OF PRODUCTION OF PEROVSKITE STRUCTURE CATALYSTS, PEROVSKITE STRUCTURE CATALYSTS AND USE THEREOF FOR HIGH TEMPERATURE DECOMPOSITION OF N2O | USTAV FYZIKALNI CHEMIE J HEYROVSKEHO AV CR V V I (CZ) | 2023-09-20 | — | — | EP | disclosed |
| CN-110997081-B | Surfactant mixtures, compositions comprising them and their use in foam concentrates for fire extinguishing | 化工产品开发公司SEPPIC | 2022-03-15 | — | — | CN | disclosed |
| CN-110249038-B | Novel surfactant mixtures, novel compositions comprising the same and their use in foam concentrates for extinguishing fires | 化工产品开发公司SEPPIC | 2021-11-26 | — | — | CN | disclosed |
| US-20210337786-A1 | COMPOSITION FOR DECONTAMINATING SOLID SURFACES | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2021-11-04 | — | — | US | disclosed |
| US-20210146183-A1 | NEW SURFACTANT MIXTURE, NEW COMPOSITION COMPRISING SAME, AND USE THEREOF IN FOAM LIQUIDS FOR FIGHTING FIRES | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2021-05-20 | — | — | US | disclosed |
| CN-112770630-A | Composition for decontaminating solid surfaces | 化工产品开发公司SEPPIC | 2021-05-07 | — | — | CN | disclosed |
| CN-110997081-A | Novel surfactant mixtures, novel compositions comprising the same and their use in foam concentrates for extinguishing fires | 化工产品开发公司SEPPIC | 2020-04-10 | — | — | CN | disclosed |
| US-20190314660-A1 | NOVEL SURFACTANT MIXTURE, NOVEL COMPOSITION COMPRISING SAME AND USE THEREOF IN FOAM LIQUIDS FOR FIGHTING FIRES | SOC DEXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2019-10-17 | — | — | US | disclosed |
| EP-3354341-A1 | METHOD OF PRODUCTION OF PEROVSKITE STRUCTURE CATALYSTS, PEROVSKITE STRUCTURE CATALYSTS AND USE THEREOF FOR HIGH TEMPERATURE DECOMPOSITION OF N2O | Ustav Fyzikalni Chemie J. Heyrovskeho AV CR, v.v.i (CZ) | 2018-08-01 | — | — | EP | disclosed |
| EP-0051659-A4 | SYSTEM FOR BICARBONATE DIALYSATE. | BABB ALBERT L (US) | 1982-11-08 | — | — | EP | disclosed |
| EP-0051659-A1 | SYSTEM FOR BICARBONATE DIALYSATE | BABB, Albert L. (US) | 1982-05-19 | — | — | EP | disclosed |
| WO-1981003180-A1 | SYSTEM FOR BICARBONATE DIALYSATE | BABB A | 1981-11-12 | — | — | WO | disclosed |