Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.60 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL20212137 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL15021193 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL176448 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL11275439 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL77648 | 1.00 | — | — | |
| Bicarbonate SCHEMBL11693424 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL15021043 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL991389 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL17477711 | 1.00 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL3791433 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768584-A | Temperature-resistant, corrosion-resistant and leakage-stopping material and preparation method thereof | 南京科赫科技有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-113355927-A | Environment-friendly plant dye for blended material and dyeing process thereof | 浙江超凡制衣有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-111304925-A | Block polyether amino silicone oil softening agent and preparation method thereof | 中山市天信助剂实业有限公司 | 2020-06-19 | — | — | CN | claimed |
| EP-3148345-B1 | METHOD FOR REFINING LIPID PHASES, AND USE | DREI LILIEN PVG GMBH&CO KG (DE) | 2026-04-29 | — | — | EP | disclosed |
| CN-119702063-A | Bio-based fatty acid methyl ester hydrogenation catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119701972-A | Bio-based fatty acid methyl ester hydrogenation catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-116768584-A | Temperature-resistant, corrosion-resistant and leakage-stopping material and preparation method thereof | 南京科赫科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116768584-A | Temperature-resistant, corrosion-resistant and leakage-stopping material and preparation method thereof | 南京科赫科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-111392753-B | Method for separating out sodium bicarbonate from deep carbonation mother liquor | 中国铝业股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-113355927-A | Environment-friendly plant dye for blended material and dyeing process thereof | 浙江超凡制衣有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-111392753-A | Method for separating out sodium bicarbonate from deep carbonation mother liquor | 中国铝业股份有限公司 | 2020-07-10 | — | — | CN | disclosed |
| WO-2015181341-A1 | METHOD FOR REFINING LIPID PHASES, AND USE | DREI LILIEN PVG GMBH & CO. KG (DE) | 2015-12-03 | — | — | WO | disclosed |
| US-8821628-B2 | Method for improving opacity | OMYA INTERNATIONAL AG (CH) | 2014-09-02 | — | — | US | disclosed |
| CN-102471607-B | Method for improving opacity | OMYA DEVELOPMENT AG | 2014-04-23 | — | — | CN | disclosed |
| EP-2292701-B1 | Method for improving opacity | OMYA DEVELOPMENT AG (CH) | 2013-09-04 | — | — | EP | disclosed |
| EP-2449035-A1 | METHOD FOR IMPROVING OPACITY | Omya Development AG (CH) | 2012-05-09 | — | — | EP | disclosed |
| US-20120097069-A1 | METHOD FOR IMPROVING OPACITY | OMYA INTERNATIONAL AG (CH) | 2012-04-26 | — | — | US | disclosed |
| EP-2292701-A1 | Method for improving opacity | Omya Development AG (CH) | 2011-03-09 | — | — | EP | disclosed |
| WO-2011001374-A1 | METHOD FOR IMPROVING OPACITY | OMYA DEVELOPMENT AG (CH) | 2011-01-06 | — | — | WO | disclosed |
| EP-0673922-A1 | Non-ionic iodinated dimers as X-ray contrast agents, process for their preparation and pharmaceutical compositions containing them | CENTRO INVESTIGACION JUSTESA IMAGEN S.A. (ES) | 1995-09-27 | — | — | EP | disclosed |